We Need Volunteers To Improve Our Understanding of the Human Immune System

Mapping Gene Regulatory Networks of Primary CD4+ T Cells Using Single-Cell Genomics and Genome Engineering

Genetic Architecture of Cell Autonomous and Multicellular Circuits

One of our research aims is to understand the genetic architecture and how the immune circuits are controlled in cells. To achieve this aim, we have examined 140 transcription factors by pooled CRISPR perturbation and scRNA-seq in 160,000 CD4+T cells. Among all the regulators, 134 were shown to affect T cell functionalization. We have further […]

MinCheol Kim

David Lee

‘AutoImmunoprofiler’ Builds on Success in Cancer Research to Advance Treatments for Autoimmune Diseases